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A highly effective anti-cancer agent (synthetic Vitamin A analog) in combination with a new drug
delivery system, has demonstrated for us a tendency to naturally collect in the pancreas.
Regardless of whether concentration in the pancreas results from passive
or active uptake, it appears possible to exploit this new finding to
target therapeutics for Pancreatic Carcinoma and stimulate high levels of drug
uptake and/or retention at this site.
Since pancreatic cancer is highly resistant to all current, non-invasive
therapies, there are only three accepted treatments: surgery, radiation
therapy, and chemotherapy. However, even these methods are inadequate as
chances of early detection are low, resulting in a 5-9 month survival
rate. Considering there is truly no effective drug treatment for pancreatic cancer, our Vitamin A analog drug
would potentially be treated as an “Orphan Drug”. This advantageous
position, in conjunction with the fact that this analog has previously
undergone considerable clinical testing, would grant SciTech a
defensible position from which to develop, manufacture, and market this
pancreatic cancer drug therapy. With estimates reaching
approximately 32,000 pancreatic cancer deaths yearly and virtually no
effective alternative treatment available, the market potential is
as extremely significant as the need urgent.
Further developmental opportunity exists
beyond this synthetic Vitamin A analog being formulated as a pancreatic
cancer drug agent. As multiple, substantiated pancreatic cancer drugs
have difficulty targeting the pancreas, the analog in conjunction with
our unique IV Retinoid technology could serve as a highly efficient delivery system for current drugs,
revolutionizing their effectiveness.
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